Diabetes complications

Trends in the Prevalence and Treatment of Diabetic Macular Edema and Vision-Threatening Diabetic Retinopathy Among Commercially Insured Adults Aged <65 Years

Diabetes CarePublished Retrospective cohort study

Authors' conclusion

Annual claims for DME or VTDR and anti-VEGF injections increased whereas those for laser photocoagulation decreased among commercially insured adults with diabetes.

Study context

Population
Commercially insured adults aged 18–64 years with diabetes, continuously enrolled in fee-for-service insurance for 24 months, IBM MarketScan Database, 2009–2018
Outcome
Annual prevalence of patients with ≥1 claims for any DME, DME or VTDR, and anti-VEGF injections and laser photocoagulation; Average annual percent change (AAPC)
Follow-up
2009-2018
Methodological detailsclaims database analysis, 10-year trend analysis
  • Claims database analysis
  • 10-year trend analysis

Main finding

As reported in the abstract

Annual prevalence · 2009 to 2018

Diabetic macular edema (DME) or vision-threatening diabetic retinopathy (VTDR) prevalence increased (2.1% to 3.4%)

AAPC 7.5%

P < 0.001

Any DME prevalence increased (0.7% to 2.6%)

AAPC 19.8%

P < 0.001

Observational data: associations, not effects.

Further findings

Annual claims for antivascular endothelial growth factor (anti-VEGF) injections · 2009 to 2018

Increase, any DME
327%
Increase, VTDR with DME
206%

Annual claims for laser photocoagulation · 2009 to 2018

Change, any DME
−68%
Change, VTDR with DME
−54%
Change, VTDR without DME
−62%

Original publication

Trends in the Prevalence and Treatment of Diabetic Macular Edema and Vision-Threatening Diabetic Retinopathy Among Commercially Insured Adults Aged <65 Years. Diabetes Care. Published 13 January 2023. doi:10.2337/dc22-1834

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