Gestational diabetes & diabetes in pregnancy
Association of Historical Redlining With Gestational Diabetes Mellitus: The Mediating Role of BMI and Area Deprivation Index
Authors' conclusion
Historic redlining is associated with an increased risk of GDM, mediated by maternal obesity and neighborhood deprivation. Future research is needed to explore the complex pathways linking redlining to pregnancy outcomes.
Study context
- Population
- Singleton pregnancies, Kaiser Permanente Southern California health records (2008–2018), residential addresses in Home Owners' Loan Corporation (HOLC)-graded zones
- Participants
- 86,834 singleton pregnancies
- Exposure
- HOLC grades B, C and D vs grade A neighborhoods
- Outcome
- GDM
Methodological detailsmixed-effect logistic regression, mediation analysis by inverse odds ratio weighting
- Mixed-effect logistic regression
- Mediation analysis by inverse odds ratio weighting
Main finding
As reported in the abstract
Risk of GDM
Each group vs AAdjusted odds ratio (95% CI)
B
1.20(0.99–1.44)
C
1.22(1.02–1.47)
D
1.30(1.08–1.57)
- Gestational diabetes mellitus (GDM) case patients
- 10,134 (11.67%)
Observational data: associations, not effects.
Further findings
Mediation of increased GDM risk in redlined areas
- Mediated by prepregnancy BMI
- 44.2%
- Mediated by area deprivation index (ADI)
- 64.5%
Original publication
Association of Historical Redlining With Gestational Diabetes Mellitus: The Mediating Role of BMI and Area Deprivation Index. Diabetes Care. Published 12 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →