Type 1 diabetes

Association of Diabetic Ketoacidosis in Childhood New-Onset Type 1 Diabetes With Day of Presentation in Germany

Diabetes CarePublished Registry-based cohort study

Authors' conclusion

New-onset T1D and DKA in children are more often diagnosed during weekdays than weekends and holidays.

Study context

Population
Children with new-onset T1D, German Prospective Diabetes Registry, last 10 years
Participants
30,717 children
Exposure
Weekends, public holidays and school vacations vs workdays
Outcome
Odds of T1D diagnosis and of diabetic ketoacidosis (DKA) by day of presentation
Methodological detailsGerman Prospective Diabetes Registry, 10 years
  • German Prospective Diabetes Registry
  • 10 years

Main finding

As reported in the abstract

T1D diagnosis
Each group vs workdaysOdds ratio (95% CI)
Weekends
0.39(0.38–0.41)
Public holidays
0.57(0.53–0.63)
School vacations
0.83(0.80–0.85)

Observational data: associations, not effects.

Further findings

OutcomeOR (CI)
Odds of DKA diagnosisWeekendsvs Workdays0.55 (0.52–0.59)
Odds of DKA diagnosisPublic holidaysvs Workdays0.73 (0.63–0.84)
Odds of DKA diagnosisSchool vacationsvs Workdays0.85 (0.80–0.90)

Results during the coronavirus pandemic

Results did not change during the coronavirus pandemic

Original publication

Association of Diabetic Ketoacidosis in Childhood New-Onset Type 1 Diabetes With Day of Presentation in Germany. Diabetes Care. Published 21 December 2023. doi:10.2337/dc23-1643

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