Association between triglyceride-glucose index and risk of cardiovascular disease among postmenopausal women
Main finding · Incident CVDResult — go to the resultHazard ratio 1.70 95% CI 1.21–2.38Authors' conclusion
Higher TyG index at baseline as a marker of insulin resistance (IR), is associated with higher risk of future CVD among postmenopausal women. The TyG index may serve as a simple and easy marker for early identification of high-risk individuals in the postmenopausal women.
Study context
- Population
- Postmenopausal women; TyG index = ln (TG [mg/dL] × fasting blood glucose [mg/dL]/2)
- Participants
- 7,741 women
- Exposure
- TyG index quartiles Q2–Q4 vs Q1
- Outcome
- Incident CVD
- Follow-up
- Median 12 years
Main finding
As reported in the abstract
Hazard ratio
1.70
95% CI 1.21–2.38
Q4vs Q1
HR 1.70 (95% CI 1.21–2.38)
Observational data: associations, not effects.
Further findings
Subgroups by age at menopause (<50 y; ≥50 y) and obesity status
- Q4 significantly associated with cardiovascular disease (CVD) risk regardless of age at menopause and obesity status
Original publication
Association between triglyceride-glucose index and risk of cardiovascular disease among postmenopausal women. Cardiovasc Diabetol. Published 30 January 2023. doi:10. 1186/ s12933-023-01753-3
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