Association between triglyceride-glucose-body mass index and risk of aortic stenosis progression in patients with non-severe aortic stenosis: a retrospective cohort study
Main finding · Aortic stenosis progressionResult — go to the resultHazard ratio 2.219 95% CI 1.086–4.537Authors' conclusion
TyG-BMI index was significantly associated with a higher risk of progression to non-severe AS. TyG-BMI index, as an effective alternative indicator of IR, can identify people at high risk of AS progression at an early stage of the disease, thereby improving the prognosis and reducing the socio-economic burden.
Study context
- Population
- Patients with non-severe aortic stenosis from ARISTOTLE; mean age 72.52 ± 11.97 years, 51.58% male
- Participants
- 190 patients
- Exposure
- High vs low triglyceride-glucose-BMI (TyG-BMI) index
- Outcome
- Progression of non-severe aortic stenosis
- Follow-up
- Median 27.48 months
Methodological detailssingle-centre, observational
- Single-centre
- Observational
Main finding
Aortic stenosis progression
Hazard ratio
2.219
95% CI 1.086–4.537
P = 0.029
High TyG-BMIvs Low TyG-BMI
HR 2.219 (95% CI 1.086–4.537); P = 0.029
As reported in the abstract
- Participants with disease progression
- 44
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association between triglyceride-glucose-body mass index and risk of aortic stenosis progression in patients with non-severe aortic stenosis: a retrospective cohort study. Cardiovasc Diabetol. Published 29 January 2025. doi:10.
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