Gestational diabetes & diabetes in pregnancy

Association between one abnormal value on 3-hour oral glucose tolerance test and adverse perinatal outcomes in twin gestation

Diabetes Res Clin PractPublished Retrospective cohort study

Authors' conclusion

Our study provides evidence that women with twin gestation and one abnormal value on the 3-hour OGTT are at an increased risk of unfavorable neonatal outcomes. This was confirmed by multivariable logistic regressions. Further research is needed to determine whether interventions such as nutritional counseling, blood glucose monitoring, and treatment with diet and medication would improve perinatal outcomes in this population.

Study context

Population
Women with twin gestation
Participants
2,597 women
Exposure
One abnormal value on 3-hour oral glucose tolerance test (OGTT) vs normal screen in twin gestation
Outcome
Adverse perinatal outcomes
Methodological detailsmulticenter
  • Multicenter

Main finding

As reported in the abstract

Adverse perinatal outcomes, one abnormal value vs normal screen

Normal screen

79.7%

One abnormal value on the OGTT

6.2%

Observational data: associations, not effects.

Original publication

Association between one abnormal value on 3-hour oral glucose tolerance test and adverse perinatal outcomes in twin gestation. Diabetes Res Clin Pract. Published 29 June 2023. doi:10.1016/j.diabres.2023.110813

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