Gestational diabetes & diabetes in pregnancy
Association between one abnormal value on 3-hour oral glucose tolerance test and adverse perinatal outcomes in twin gestation
Authors' conclusion
Our study provides evidence that women with twin gestation and one abnormal value on the 3-hour OGTT are at an increased risk of unfavorable neonatal outcomes. This was confirmed by multivariable logistic regressions. Further research is needed to determine whether interventions such as nutritional counseling, blood glucose monitoring, and treatment with diet and medication would improve perinatal outcomes in this population.
Study context
- Population
- Women with twin gestation
- Participants
- 2,597 women
- Exposure
- One abnormal value on 3-hour oral glucose tolerance test (OGTT) vs normal screen in twin gestation
- Outcome
- Adverse perinatal outcomes
Methodological detailsmulticenter
- Multicenter
Main finding
As reported in the abstract
Adverse perinatal outcomes, one abnormal value vs normal screen
Normal screen
79.7%
One abnormal value on the OGTT
6.2%
Observational data: associations, not effects.
Original publication
Association between one abnormal value on 3-hour oral glucose tolerance test and adverse perinatal outcomes in twin gestation. Diabetes Res Clin Pract. Published 29 June 2023. doi:10. 1016/ j. diabres. 2023. 110813
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