Gestational diabetes & diabetes in pregnancy
Assessing the impact of pregnancy planning on obstetric and perinatal outcomes in women with pregestational diabetes mellitus
Authors' conclusion
Pregnancy planning in PGDM women improved glycemic control and HbA1c levels. Limited impact on obstetric and perinatal outcomes suggests scope for other focused interventions to optimize maternal and fetal health.
Study context
- Population
- Pregnant women with pregestational DM (pregestational diabetes mellitus (PGDM)) treated at one centre, 2012–201826.6 % planned
- Participants
- 425 women
- Exposure
- Planned vs unplanned pregnancy
- Outcome
- Pregestational HbA1c
- Follow-up
- Pregestational
Methodological detailsobservational, single-centre
- Observational
- Single-centre
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | Values | P value |
|---|---|---|
| HbA1c at first prenatal visitSignificantly lower in the planned pregnancy group | Planned pregnancy 6.39 % | P < 0.001 |
| HbA1c at end of pregnancyDifferences persisted; lower with planned pregnancy | Planned pregnancy 6.09 % | P = 0.006 |
Birth weight >4000 g and >4500 g
- Better glycemic control associated with a non-significant decrease in fetuses with birth weight >4000 g and >4500 g
Other morbidity events, maternal outcomes, cesarean section rate
- No significant effects on other morbidity events, maternal outcomes or cesarean section rate
BMI
- Women with planned pregnancies had lower BMI
Original publication
Assessing the impact of pregnancy planning on obstetric and perinatal outcomes in women with pregestational diabetes mellitus. Diabetes Res Clin Pract. Published 27 February 2024. doi:10.
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