Health-Related Quality of Life and Health Utility After Metabolic/Bariatric Surgery Versus Medical/Lifestyle Intervention in Individuals With Type 2 Diabetes and Obesity: The ARMMS-T2D Study
Primary result · SF-36 Physical Component Score (PCS) changeResult — go to the resultDifference 3.32Authors' conclusion
Metabolic surgery produces sustained weight loss and improves PCS, general health, physical functioning, vitality, and HU in individuals with type 2 diabetes and obesity compared with medical therapy up to 12 years after intervention.
Study context
- Population
- Individuals with T2D and obesity in the ARMMS-T2D study; baseline mean ± SD age 49.2 ± 8.0 years, 68.4% female, BMI 36.3 ± 3.4 kg/m², HbA1c 8.7 ± 1.6%
- Participants
- 228 individuals
- Comparison
- Metabolic/bariatric surgery (MBS) vs medical/lifestyle intervention
- MBSn = 152
- Medical/lifestyle intervention (MLI)n = 76reference
Methodological detailslong-term follow-up up to 12 years
- Long-term follow-up up to 12 years
Primary result
SF-36 Physical Component Score (PCS) change · over 12 years
Difference
3.32
P < 0.001
Change by group
MBS
+2.37
± 0.53
MLI
−0.95
± 0.73
As reported in the abstract
Further findings
| Outcome | MBS | MLI | Difference | P value |
|---|---|---|---|---|
| SF-36 Mental Component Score (MCS) change · during follow-up± 0.97; similar between groups | −0.21 ± 0.61 | −0.89 ± 0.84 | 0.68 | P = 0.48 |
| Health utility (SF-6D) change · over 12 years± 0.01; greater improvement with MBS | +0.02 ± 0.01 | −0.01 ± 0.01 | 0.03 | P = 0.003 |
- SF-36 domains: general health, physical functioning, vitality · better general health with MBS
- P < 0.001
- SF-36 domains: general health, physical functioning, vitality · better physical functioning with MBS
- P = 0.001
- SF-36 domains: general health, physical functioning, vitality · better vitality with MBS
- P = 0.003
- BMI reduction and correlation with PCS — Correlation of BMI reduction with improved PCS (r) · greater BMI reduction with MBS
- r = −0.43; P < 0.001 · P < 0.001
BMI reduction and correlation with PCS
- Change in PCS not associated with change in HbA1c
Original publication
Health-Related Quality of Life and Health Utility After Metabolic/Bariatric Surgery Versus Medical/Lifestyle Intervention in Individuals With Type 2 Diabetes and Obesity: The ARMMS-T2D Study. Diabetes Care. Published 4 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →