Appropriate screening interval to detect the development of chronic metabolic diseases
Authors' conclusion
In adults aged 30-40, the screening interval of metabolic disorders should be individualized based on the baseline metabolic derangement. An individual with borderline values may need an annual screening.
Study context
- Population
- Adults without diabetes mellitus (DM), hypertension, dyslipidemia and abdominal obesity who underwent health examinations (2005–2019) in Korea; grouped by baseline fasting glucose, LDL-C, blood pressure (BP) and waist circumference (WC)
- Participants
- 222,413 adults
- Outcome
- Time to develop metabolic disorders (time until 10% of participants developed each disorder) by baseline group
Main finding
As reported in the abstract
Time until 10% of participants developed each metabolic disorder, by baseline category · median follow-up 4.94 years
- DM, fasting glucose 100-110 mg/dL
- 8.32 years (95 %CI 8.22-8.41)
- DM, fasting glucose 110-120 mg/dL
- 3.01 years (2.89-3.31)
- DM, fasting glucose 120-125 mg/dL
- 1.11 years (1.03-1.25)
- Hypertension, BP 120/70 mmHg
- 8.40 years (8.33-8.45)
- Hypertension, BP 120/70-130/80 mmHg
- 6.33 years (6.20-6.47)
- Hypertension, BP 130/80-140/90 mmHg
- 1.99 years (1.97-2.00)
- Dyslipidemia, LDL-C 100-120 mg/dL
- 5.99 years (5.94-6.04)
- Dyslipidemia, LDL-C 120-140 mg/dL
- 2.84 years (2.77-2.90)
- Dyslipidemia, LDL-C 140-160 mg/dL
- 1.36 years (1.30-1.44)
- Abdominal obesity, baseline WC < 80(W)/85(M) cm
- 4.62 years (4.41-4.80)
- Abdominal obesity, baseline WC < 85(W)/90(M) cm
- 1.67 years (1.64-1.69)
Observational data: associations, not effects.
Original publication
Appropriate screening interval to detect the development of chronic metabolic diseases. Diabetes Res Clin Pract. Published 3 April 2023. doi:10.
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