Associations between anthropometric measures of obesity and prediabetes risk: A dose–response meta‐analysis of cohort studies
Authors' conclusion
This study supports the use of BMI as a risk marker for prediabetes, whereas WC showed no significant association.
Study context
- Population
- Cohort studies assessing body mass index (BMI) or waist circumference (WC) and development of prediabetes during longitudinal follow-up; databases searched through 3 May 202528 studies
- Comparison
- BMI and WC and prediabetes risk
- Outcome
- Prediabetes risk (development of prediabetes during the longitudinal investigation)
Methodological details8434 records retrieved; 28 included in the meta-analysis
- 8434 records retrieved; 28 included in the meta-analysis
Pooled result
As reported in the abstract
Prediabetes risk
BMI as continuous variable, RR
1.10
95% CI 1.03, 1.17
BMI as categorical variable, RR
1.52
95% CI 1.19, 1.94
Dose-response: linear association; increase in prediabetes risk per 1-unit increase in BMI
4.6%
Original publication
Associations between anthropometric measures of obesity and prediabetes risk: A dose–response meta‐analysis of cohort studies. Diabetes Obes Metab. Published 5 January 2026. doi:10.
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