Application of Calcaneal Ultrasonography for Long‐Term Fracture Risk Assessment in Diabetic Osteopathy
Authors' conclusion
Calcaneal QUS may represent an effective tool in assessment of fracture risk among patients with T2DM.
Study context
- Population
- Patients with T1D or T2D who underwent calcaneal quantitative ultrasound (QUS) evaluation in 2013231 interviewed in 2023
- Participants
- 300 patients
- Exposure
- Calcaneal QUS parameters in fractured vs non-fractured patients with T1D and T2D
- T1DMn = 106
- T2DMn = 194
- Outcome
- Long-term risk of fragility fractures estimated by calcaneal QUS
- Follow-up
- 2013-2023
Methodological details10-year follow-up interview
- 10-year follow-up interview
Main finding
As reported in the abstract
Association of QUS parameters (BUA, SOS, SI) with new MOF · 10 years
- New clinical fragility fracture
- 31 patients (13%)
- New major osteoporotic fractures (MOF)
- 14 patients (6%)
- BUA significantly associated with new MOF in T2DM
- p < 0.01
Observational data: associations, not effects.
Further findings
Baseline fragility fracture at any site
- At least one fragility fracture
- 39 patients (13%)
- Fractured patients had significantly lower QUS parameters than non-fractured, in both T1DM and T2DM
- P < 0.0001
Original publication
Application of Calcaneal Ultrasonography for Long‐Term Fracture Risk Assessment in Diabetic Osteopathy. Clin Endocrinol (Oxf). Published 1 April 2025. doi:10.
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