Obesity

Anthropometry and Body Composition in Childhood: Follow‐Up of a Randomised, Double‐Blinded Controlled Trial With a Modified, Low‐Protein Infant Formula During Infancy

Pediatr ObesPublished Follow-up of a randomised controlled trial

Primary result · Anthropometry and body compositionResult — go to the resultDifference in mean fat-free mass −1240 g 95% CI −1889 to −591

Authors' conclusion

Feeding a mLP formula during early life did not have beneficial effects on body composition in a subset of infants studied at age 6 year.

Study context

Population
Healthy term-born infants106 measured at 6y
Participants
90 / 88 / 67
Comparison
Modified low-protein infant formula (mLP) vs control infant formula (CTRL) up to 6 months; breastfed reference
  • mLPn = 90
  • CTRLn = 88reference
  • Breastfed (BF)n = 67
Primary endpoint
Growth and body composition (anthropometry; air-displacement plethysmography)
Follow-up
6 years
Methodological detailsdouble-blind
  • Double-blind

Primary result

Anthropometry and body composition

Difference in mean fat-free mass

−1240 g

95% CI −1889 to −591

P < 0.001

mLPvs CTRL
difference in mean fat-free mass −1240 g (95% CI −1889 to −591); P < 0.001

As reported in the abstract

Original publication

Anthropometry and Body Composition in Childhood: Follow‐Up of a Randomised, Double‐Blinded Controlled Trial With a Modified, Low‐Protein Infant Formula During Infancy. Pediatr Obes. Published 4 July 2025. doi:10.1111/ijpo.70038

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