The effects of protein supplementation on body composition after bariatric surgery: a systematic review and meta‐analysis of randomized controlled trials
Authors' conclusion
Based on moderate- to low-certainty evidence, our findings suggest that although protein supplementation may improve weight and some body composition metrics, it does not influence overall BMI and lean body mass. More research is needed to recommend protein supplementation after MBS.
Study context
- Population
- Patients after metabolic bariatric surgery (MBS)10 RCTs
- Comparison
- Protein or amino acid supplementation vs control
- Outcome
- Anthropometric measures and body composition
Methodological detailssystematic search up to January 2024, weighted mean difference
- Systematic search up to January 2024
- Weighted mean difference
Pooled result
As reported in the abstract
Protein vs ControlEstimate (95% CI)P value
GRADE = moderate
WMD (weight) −1.31 kg(−1.93 to −0.69)
P < 0.001GRADE = low
WMD (muscle mass) 1.33 kg(0.1–2.57)
P = 0.035GRADE = low
WMD (fat-free mass) 1.74 kg(0.46–3.01)
P = 0.01GRADE = low
WMD (fat mass) −3.91 kg(−4.10 to −0.59)
P = 0.01Original publication
The effects of protein supplementation on body composition after bariatric surgery: a systematic review and meta‐analysis of randomized controlled trials. Obesity (Silver Spring). Published 1 May 2025. doi:10.
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