Gestational diabetes & diabetes in pregnancy
Antenatal Corticosteroids in Gestational Diabetes: A Systematic Review of Glycemic Response and Management Strategies
Authors' conclusion
ACS exposure in GDM is associated with a predictable but variable, transient deterioration in maternal glycaemia. GDM-specific evidence suggests that structured pregnancy-adapted monitoring and insulin-adjustment pathways may help attenuate post-ACS hyperglycaemia. However, the evidence remains heterogeneous and largely observational.
Study context
- Population
- Individuals with gestational diabetes mellitus (GDM) exposed to antenatal corticosteroids (ACS)20 studies
- Outcome
- Glycaemic response and management after ACS
Methodological detailsPRISMA, Embase, MEDLINE and CENTRAL searched October 2025
- PRISMA
- Embase, MEDLINE and CENTRAL searched October 2025
Pooled result
As reported in the abstract
- Hyperglycaemia typically emerged within
- 9-16 h
- Hyperglycaemia peaked over the subsequent
- 24-72 h
- Hyperglycaemia often persisted up to
- 5 days
- Insulin initiation among those on medical nutrition therapy or oral hypoglycaemic agents at baseline
- 13% to 91%
- Insulin dose escalation required among those already using insulin
- 67%-88%
- Mean insulin dose increases typically
- 47% to 91%
Original publication
Antenatal Corticosteroids in Gestational Diabetes: A Systematic Review of Glycemic Response and Management Strategies. Diabetes Obes Metab. Published 9 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →