Age of Type 1 Diabetes Onset and Dementia Risk: A Swedish Nationwide, Register‐Based Cohort Study
Authors' conclusion
Type 1 diabetes onset before age 10 is associated with an increased risk of all-cause dementia compared to onset between ages 18 and 30.
Study context
- Population
- Individuals with T1D from the Swedish National Diabetes Register; mean age 33.0 (SD 14.0) years; 44% female
- Participants
- 43,440 individuals
- Exposure
- Age at T1D onset <10 years and 10-17 years vs 18-30 years
- < 10 yearsn = 11,776
- 10-17 yearsn = 15,846
- 18-30 yearsn = 15,818reference
- Outcome
- All-cause dementia (including Alzheimer's disease, vascular dementia and non-Alzheimer's-non-vascular dementia), ascertained as ICD-10 codes
- Follow-up
- Median 29.3 [17.6-43.7] years
Main finding
As reported in the abstract
All-cause dementia
Each group vs 18-30 yearsHazard ratio (95% CI)
< 10 years
1.37(1.08–1.73)
10-17 years
1.04(0.85–1.26)
- Developed all-cause dementia, whole cohort
- 530 (1.2%)
Observational data: associations, not effects.
Original publication
Age of Type 1 Diabetes Onset and Dementia Risk: A Swedish Nationwide, Register‐Based Cohort Study. Diabetes Obes Metab. Published 19 July 2026. doi:10.
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