Determinants of health‐related quality of life in adults with type 1 diabetes: The predominant role of sleep among lifestyle parameters
Authors' conclusion
Lifestyle indices (MLI, PLI) were associated with better compared to worse HrQoL in PwT1D; however, this was entirely driven by sleep quality, with poor sleep linked to lower physical, mental and overall HrQoL.
Study context
- Population
- Adults with T1D; median age 38.0 (25.0, 48.8) years; 42.4% men; median T1D duration 19.0 (10.0, 29.0) years; HbA1c 7.4% (6.8, 8.2)
- Participants
- 236 adults
- Exposure
- Lifestyle indices and individual lifestyle parameters vs health-related quality of life (HrQoL)
- Outcome
- Overall quality of life (worse, average or better) by lifestyle indices (MLI, PLI) and individual components
Main finding
As reported in the abstract
Better vs worse OQoL with higher lifestyle index scores (adjusted)
Better OQoL vs Worse OQoLOdds ratio (95% CI)
MLI score
1.41(1.15–1.72)
PLI score
1.40(1.15–1.70)
Observational data: associations, not effects.
Further findings
Poor sleep quality (only lifestyle parameter associated with HrQoL in individual analyses)
- Overall quality of life (OQoL): OR
- 0.55 (95% CI 0.45-0.68)
- Physical component: OR
- 0.89 (95% CI 0.82-0.98)
- Mental component: OR
- 0.73 (95% CI 0.65-0.82)
Original publication
Determinants of health‐related quality of life in adults with type 1 diabetes: The predominant role of sleep among lifestyle parameters. Diabet Med. Published 19 July 2026. doi:10.
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