Obesity

Adolescent body mass index and cognitive performance: a nationwide study of 2.48 million Israeli adolescents

Eur J EndocrinolPublished Cross-sectional study

Authors' conclusion

Obesity, is associated with increased odds for a lower cognitive performance, and the inability to fully achieve cognitive potential, regardless of sociodemographic background.

Study context

Population
All Israeli-born adolescents aged 16 to ≤20 years at pre-recruitment evaluation for military service, 1967–2018; 1,459,522 males and 1,027,953 females445,385 with parental scores
Exposure
Body mass index (BMI) categories vs normal weight
Outcome
Cognitive performance by validated IQ-equivalent test, standardized to year- and sex-Z-score; low cognitive score (below 25th percentile)
Methodological detailsnationwide, population-based, Multinomial logistic regression models
  • Nationwide
  • Population-based
  • Multinomial logistic regression models

Main finding

As reported in the abstract

Low cognitive score (<25th percentile), male adolescents
Each group vs normal weightOdds ratio (CI)
Underweight
1.45(1.43–1.48)
Overweight
1.13(1.12–1.15)
Mild obesity
1.36(1.33–1.39)
Severe obesity
1.58(1.52–1.64)

Observational data: associations, not effects.

Further findings

Low cognitive score, females

Similar findings were observed in females

Adjusted models (sociodemographic confounders, coexisting morbidities, parental cognitive scores)

Point estimates overall consistent in adjusted models, both sexes

Lower-than-expected cognitive score based on parents' data

Abnormal BMI had higher ORs, depending on obesity severity

Original publication

Adolescent body mass index and cognitive performance: a nationwide study of 2.48 million Israeli adolescents. Eur J Endocrinol. Published 5 July 2023. doi:10.1093/ejendo/lvad075

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