Acromegaly increases depressive symptoms and reduces quality of life of cohabitants
Authors' conclusion
The chronic process of acromegaly and the external appearance of patients with this disease can negatively affect both the patients and the people living with them. Physicians being aware of this effect and taking counteractive measures may contribute positively to the course of acromegaly.
Study context
- Population
- Patients with acromegaly and their cohabitants84 patients · 84 cohabitants
- Exposure
- Cohabitants affected vs not affected by the acromegalic appearance
- Outcome
- Cohabitants' anxiety (BAI), depression (BDI), caregiver burden (ZBI) and quality of life (QoL) (SF-36) by effect of acromegalic appearance
Main finding
As reported in the abstract
- Affected vs Not affected: P < 0.001 for all
- Affected vs Not affected: P = 0.015
Observational data: associations, not effects.
Further findings
Patients with acromegalic appearance
- Patients with acromegalic appearance
- 69 (n = 84, 82.1%)
Correlation of cohabitants' scores with patients' AcroQoL
- Beck Anxiety Inventory (BAI) vs AcroQoL
- r=−0.535, p < 0.001
- Beck Depression Inventory (BDI) vs AcroQoL
- r=−0.592, p < 0.001
- ZBI vs AcroQoL
- r=−0.465, p < 0.001
- SF-36 vs AcroQoL
- r = 0.387, p < 0.001
Original publication
Acromegaly increases depressive symptoms and reduces quality of life of cohabitants. Pituitary. Published 30 December 2023. doi:10.
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