Thyroid disease

A Small Opening in the Storm Clouds: Overview of the Registry-based Study on the Management of Thyroid Storm

J Clin Endocrinol MetabPublished Editorial commentary on a prospective multicentre registry-based study

Authors' conclusion

Adherence to treatment guidelines correlates with lower mortality rates

Study context

Population
Patients with new-onset thyroid storm (TS)new-onset TS
Participants
110 patients
Exposure
Outcomes of new-onset TS vs previous comparable studies; efficacy of the 2016 Guidelines
Outcome
Prognosis and outcome of TS
Methodological detailsmulticenter, register-based
  • Multicenter
  • Register-based

Main finding

As reported in the abstract

  • Higher APACHE II scores and, overall, improved TS prognosis vs previous comparable studies
  • Significant correlations of lower BMI, postresuscitation shock and fever with outcomes
  • Most patients received MMI and potassium iodide; timely administration linked to lower fatality rates

Observational data: associations, not effects.

Original publication

A Small Opening in the Storm Clouds: Overview of the Registry-based Study on the Management of Thyroid Storm. J Clin Endocrinol Metab. Published 9 August 2024. doi:10.1210/clinem/dgae543

Composed by AI from the published abstract and checked against it. How Briefs are made →

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