A systematic review of subclinical hyperthyroidism guidelines: a remarkable range of recommendations
Authors' conclusion
This review underscores the existing variability in (inter)national guidelines concerning subclinical hyperthyroidism. There isa need for clear recommendations in guidelines considering diagnostic workup, treatment, and follow-up of subclinical hyperthyroidism. In order to establish this, future research should focus on determining clear and evidence-based intervention thresholds.
Study context
- Population
- International clinical practice guidelines with recommendations on SCH (subclinical hyperthyroidism), published 2007–2021
- Participants
- 22 guidelines
- Outcome
- Variation in guideline recommendations on diagnostic workup, treatment and follow-up
Methodological detailsPRISMA, Appraisal of Guidelines for Research & Evaluation (AGREE) II quality assessment
- PRISMA
- AGREE II quality assessment
Pooled result
As reported in the abstract
Recommended monitoring intervals for follow-up
3 to 12 months
Original publication
A systematic review of subclinical hyperthyroidism guidelines: a remarkable range of recommendations. Eur Thyroid J. Published 13 June 2024. doi:10.
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