A randomized controlled trial to reduce post-cessation weight gain

Int J Obes (Lond)Published Randomised controlled trial

Authors' conclusion

Results indicated the Stability and the Loss interventions were effective for preventing post-smoking cessation weight gain, with the Loss group having the benefit of sustained weight loss. These interventions may be helpful to implement to combat weight gain and potentially facilitate smoking cessation.

Study context

Population
Adults smoking ≥5 cigarettes/day for the last year and interested in quitting, initially recruited from Memphis, TN, USA, expanded nationally with COVID-19 onset; 2018–2022276 completed 12-month follow-up
Participants
305 adults
Comparison
Weight stability and weight loss interventions vs self-guided bibliotherapy weight management
Primary endpoint
Weight change
Follow-up
12-month follow-up

Primary result

As reported in the abstract

Loss

−2.01

SE 1.58 · kg

Stability

−0.30

SE 1.56 · kg

Bibliotherapy

+1.08

SE 1.49 · kg

Loss vs Bibliotherapy: P = 0.0004 · Stability vs Bibliotherapy: P = 0.17

Further findings

Self-reported smoking cessation · each time point

No significant differences between groups at each time point except at eight-month follow-up
P = 0.005

Original publication

A randomized controlled trial to reduce post-cessation weight gain. Int J Obes (Lond). Published 25 February 2023. doi:10.1038/s41366-023-01286-5

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