Obesity

A Primary Care–Based Weight Navigation Program

JAMA Netw OpenPublished Retrospective cohort study

Authors' conclusion

The findings of this cohort study suggest that WNP is feasible and associated with greater WMT use and weight loss than matched controls. The WNP warrants evaluation in a large-scale trial.

Study context

Population
Adults with obesity and ≥1 weight-related condition from intervention and control sites, large academic health system, Midwestern US; 68.6% female, mean age 49.5 yearspropensity matched
Participants
264 adults
Exposure
Primary care–based weight navigation program vs matched controls
  • Weight navigation program (WNP)n = 132
  • Matched controlsn = 132reference
Outcome
Feasibility measures, including rates of referral to and engagement in the WNP
Methodological detailsevaluation of a quality improvement program, propensity matched, difference-in-differences analysis, Program conducted October 1, 2020, to September 30, 2021
  • Evaluation of a quality improvement program
  • Propensity matched
  • Difference-in-differences analysis
  • Program conducted October 1, 2020, to September 30, 2021

Main finding

As reported in the abstract

Feasibility among 1159 WNP-eligible patients

Referred to the WNP

219

18.9%

Completed a WNP visit

132

11.4%

Observational data: associations, not effects.

Secondary outcomes

OutcomeDifference (kg) (95% CI)P value
Weight loss (kg) · 12 monthsGreater weight loss with WNP; difference-in-differences4.9 (2.11–7.76)P < 0.001
OutcomeDifference (95% CI)P value
Percentage weight loss · 12 monthsGreater weight loss with WNP4.4% (2.2%–6.4%)P < 0.001
OutcomeOR (95% CI)
≥5% weight loss · 12 months2.90 (1.54–5.58)
≥10% weight loss · 12 months7.19 (2.55–25.9)

Referral to bariatric surgery

P = 0.02

Referral to low-calorie meal replacement program

P < 0.001

Referral to Mediterranean-style diet and activity program

P = 0.002

OutcomeAverage marginal effects (95% CI)
≥5% weight loss · 12 months21.2% (8.8%–33.6%)
≥10% weight loss · 12 months17.4% (8.7%–26.2%)

Antiobesity medication prescribing

No between-group differences in antiobesity medication prescribing

Original publication

A Primary Care–Based Weight Navigation Program. JAMA Netw Open. Published 1 May 2024. doi:10.1001/jamanetworkopen.2024.12192

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