A medical chart audit to assess endocrinologist perceptions of the burden of endogenous Cushing’s syndrome
Authors' conclusion
Endocrinologists recognized that patients with CS suffered from a debilitating condition with a high symptomatic and HRQoL burden and reported that improvement in HRQoL was the key treatment attribute influencing their treatment choices. This study highlights unmet needs for patients with CS. Patients with CS have a high rate of morbidity and comorbidity, even after treatment.
Study context
- Population
- Treated patients with confirmed endogenous Cushing's syndrome (CS), charts abstracted by qualified endocrinologists; mean age 46.5 ± 13.4 years, 60:40 female:male, mean CS duration 4.1 years69 endocrinologists
- Participants
- 273 patients
- Outcome
- Endocrinologist perceptions and patient burden of CS
Methodological detailsretrospective medical chart audit, survey of endocrinologists, case report form, web-enabled questionnaire
- Retrospective medical chart audit
- Survey of endocrinologists
- Case report form
- Web-enabled questionnaire
Main finding
As reported in the abstract
Improvement in health-related quality of life (HRQoL) rated the most important treatment attribute (mean score; scale 1 = Not at all important to 9 = Extremely important)
7.8
Observational data: associations, not effects.
Original publication
A medical chart audit to assess endocrinologist perceptions of the burden of endogenous Cushing’s syndrome. Pituitary. Published 8 January 2024. doi:10.
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