A long-term follow-up of treatment for young children with obesity: a randomized controlled trial
Authors' conclusion
The intensive parent-support early childhood obesity intervention led to better weight status outcomes over time, though BMI-SDS alone did not reflect this. Further research should investigate how to assess weight changes in growing children.
Study context
- Population
- Families of 4- to 6-year-olds with obesity, More and Less study, Sweden (2012–2017); non-Swedish origin 59%, university degree 40%114 with 48-month data
- Participants
- 171 families
- Comparison
- Parent support program with boosters (PGB) or without (PGNB) vs standard outpatient treatment (ST)
- Primary endpoint
- BMI-SDS
- Follow-up
- 48 months
Methodological details3-arm, modified intention-to-treat, 48-month follow-up
- 3-arm
- Modified intention-to-treat
- 48-month follow-up
Primary result
As reported in the abstract
Change in BMI-SDS · 48 months (mean 50 months, range 38-67 months)
| Group | Value | p |
|---|---|---|
| PGB | mean −0.45 (95% CI −0.18–-0.73) | p < 0.001 |
| PGNB | mean −0.34 (95% CI −0.13–-0.55) | p < 0.001 |
| ST | mean −0.25 (95% CI −0.10–-0.40) | p < 0.001 |
Value
PGBmean −0.45 (95% CI −0.18–-0.73)
PGNBmean −0.34 (95% CI −0.13–-0.55)
STmean −0.25 (95% CI −0.10–-0.40)
p
PGBp < 0.001
PGNBp < 0.001
STp < 0.001
Secondary outcomes
| Outcome | PGB | PGNB | ST | RR (CI) | P value | |
|---|---|---|---|---|---|---|
| Clinically significant BMI-SDS reduction ≥0.5 · 48 monthsPGBvs ST | 53.7% | 46.6% | 33.0% | 2.03 (1.27–3.27) | P = 0.003 | |
| 0.20.5125Relative risk (log scale) |
| Outcome | PGB | PGNB | ST | P value |
|---|---|---|---|---|
| Clinically significant BMI-SDS reduction ≥0.5 · 48 monthsPGB vs PGNB · no difference | P = 0.113 | |||
| %IOTF25 (percent distance above overweight cut-off) · 48 monthsPGB vs ST · significantly lower with PGB | 4.50 (95% CI −1.64–10.63) | — not stated in the abstract | 11.92 (95% CI 8.40–15.44) | P = 0.043 |
— not stated in the abstract
%IOTF25 (percent distance above overweight cut-off) · 48 months
- %IOTF25 unchanged from baseline for PGB
Sociodemographics and attendance (three-way interactions)
- Sociodemographics or attendance had no effect
Original publication
A long-term follow-up of treatment for young children with obesity: a randomized controlled trial. Int J Obes (Lond). Published 25 October 2023. doi:10.
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