A Comparison of Continuous Glucose Monitoring-Measured Time-in-Range 70–180 mg/dL Versus Time-in-Tight-Range 70–140 mg/dL
Authors' conclusion
TIR and TITR are highly correlated, although the relationship is nonlinear. With knowledge of TIR, TITR can be estimated with reasonable precision.
Study context
- Population
- Participants with T1D (9 studies, 912 participants) and T2D (2 studies, 184 participants) with CGM dataT1D 912
- Participants
- 912 vs 184
- Comparison
- TIR 70-180 mg/dL vs TITR 70-140 mg/dL
- T1Dn = 912
- T2Dn = 184
- Outcome
- Relationship between CGM-measured TIR 70-180 mg/dL and TITR 70-140 mg/dL
Methodological detailsblinded or unblinded Dexcom sensors, stratified by coefficient of variation (CV) and TBR
- Blinded or unblinded Dexcom sensors
- Stratified by CV and TBR
Pooled result
As reported in the abstract
TIR-TITR relationship
Correlation between TIR and TITR
0.94
Further pooled results
- TITR higher for a given TIR in T2D than T1D; differences minimized after adjusting for CV or TBR (both higher with T1D)
Original publication
A Comparison of Continuous Glucose Monitoring-Measured Time-in-Range 70–180 mg/dL Versus Time-in-Tight-Range 70–140 mg/dL. Diabetes Technol Ther. Published 13 October 2023. doi:10. 1089/ dia. 2023. 0380
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