Diabetes technology

Effects of continuous glucose monitoring on glycaemic control in type 2 diabetes: A systematic review and network meta‐analysis of randomized controlled trials

Diabetes Obes MetabPublished Systematic review and network meta-analysis of randomised controlled trials

Pooled result · HbA1cResult — go to the resultMD −0.31 95% CI −0.45 to −0.18

Authors' conclusion

CGM could provide T2DM with greater benefits in glycaemic management compared with SMBG, particularly in patients using real-time CGM. These findings provide an updated perspective on previous research and offer guidance for CGM use in T2DM.

Study context

Population
Outpatients with T2DM; RCTs from 1 January 2000 until 31 December 2022 (PubMed, Web of Science, EMBASE, OVID)
Participants
1,425 outpatients11 studies
Comparison
Continuous glucose monitoring (CGM) vs self-monitoring of blood glucose (SMBG)
Outcome
Glycated haemoglobin
Methodological detailstraditional and network meta-analyses
  • Traditional and network meta-analyses

Pooled result

HbA1c

MD

−0.31

95% CI −0.45 to −0.18

CGMvs SMBG
MD −0.31 (95% CI −0.45 to −0.18)

As reported in the abstract

Further pooled results

OutcomeMD (%) (95% CI)
TAR−9.06 (−16.00 to −2.11)
TBR−0.30 (−0.49 to −0.12)
TIR8.49 (3.96–13.02)

Network meta-analysis

rtCGM can improve glycaemic control of patients with T2DM to the most extent

Original publication

Effects of continuous glucose monitoring on glycaemic control in type 2 diabetes: A systematic review and network meta‐analysis of randomized controlled trials. Diabetes Obes Metab. Published 12 October 2023. doi:10.1111/dom.15328

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