A 7‐year prospective analysis of sustained benefits of multicomponent risk assessment and data‐driven care in patients with type 2 diabetes: The Malaysian Joint Asia Diabetes Evaluation (JADE) Program
Primary result · Attaining ≥2 ABC targetsResult — go to the resultOdds ratio 1.57 95% CI 1.02–2.41Authors' conclusion
Technology-assisted multicomponent risk assessment and data-driven care for 1-year identified high-risk patients and improved outcomes after 7 years.
Study context
- Population
- Patients with T2D from Malaysia in a 1-year JADE Program (2012–2015), re-assessed 2020–2022826 returned
- Participants
- 1,196 patients
- Comparison
- Comprehensive assessment (CA) + R + T vs CA-only
- Primary endpoint
- Attainment of ≥2 ABC targets (HbA1c <7%, BP <130/80 mmHg, LDL-C <2.6 mmol/L)
- Follow-up
- 7.5 ± 0.5 years
Methodological detailsprospective, 3-arm, inverse probability weighting
- Prospective
- 3-arm
- Inverse probability weighting
Primary result
Attaining ≥2 ABC targets
Odds ratio
1.57
95% CI 1.02–2.41
P = 0.041
CA + R + Tvs CA-only
OR 1.57 (95% CI 1.02–2.41); P = 0.041
As reported in the abstract
Further findings
| Outcome | Incidence rate ratio (CI) | P value | |
|---|---|---|---|
| Any diabetes-related endpoints, participants without complications at baselineCA + R + Tvs CA-only | 0.89 (0.78–1.00) | P = 0.043 | |
| 0.512Incidence rate ratio (log scale) |
Other predictors of attaining ≥2 ABC targets
- Age, OR
- 1.05 (1.04-1.07, p < 0.001) (95% CI)
- Diabetes duration, OR
- 0.97 (0.95-0.99, p = 0.003) (95% CI)
- JADE risk category 3 vs category 1 and 2, OR
- 0.41 (0.26-0.66), p < 0.001 (95% CI)
- JADE risk category 4 vs category 1 and 2, OR
- 0.22 (0.12-0.38), p < 0.001 (95% CI)
Follow-up status · 7.5 ± 0.5 years
- Died
- 138 (11.5%)
- Defaulted
- 232 (19.4%)
- Returned
- 826 (69.1%)
Original publication
A 7‐year prospective analysis of sustained benefits of multicomponent risk assessment and data‐driven care in patients with type 2 diabetes: The Malaysian JADE Program. Diabetes Obes Metab. Published 15 September 2025. doi:10.
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