Women With Polycystic Ovary Syndrome and Excess Body Fat Exhibit Atypical Sympathetic Autonomic Modulation That is Partially Reversed by Aerobic Physical Training
Authors' conclusion
PCOS affects vagal modulation; however, this effect may be masked at elevated levels of body fat. Additionally, the combination of excess body fat with endocrine-metabolic dysregulation appears to reduce sympathetic modulation, possibly due to sympathetic drive hyperactivity. APT positively affected HRV in both PCOS groups.
Study context
- Population
- Women with and without polycystic ovary syndrome (PCOS) with different percentages of body fat
- Comparison
- Women with vs without PCOS, by body fat percentage (22%–29% vs 30%–37%), before and after 16 weeks of aerobic physical training
Primary result
As reported in the abstract
Autonomic modulation of HRV · before APT
- PCOS (22%-29%) had lower vagal modulation than CONTROL (22%-29%)
- No significant differences between CONTROL (30%-37%) and PCOS (30%-37%)
- PCOS (30%-37%) had lower sympathetic modulation than PCOS (22%-29%)
Further findings
Heart rate variability (HRV) after aerobic physical training · after 16 weeks of aerobic physical training (APT)
- PCOS (22%-29%) increased in vagal modulation
- PCOS (30%-37%) increased in sympathetic modulation
Original publication
Women With Polycystic Ovary Syndrome and Excess Body Fat Exhibit Atypical Sympathetic Autonomic Modulation That is Partially Reversed by Aerobic Physical Training. Clin Endocrinol (Oxf). Published 11 November 2024. doi:10.
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