What Is the Influence of HIV Serostatus on HbA1c? A Prospective Analysis Using Continuous Glucose Monitoring
Authors' conclusion
We performed a comprehensive assessment of glycemia to assess whether HIV serostatus influences HbA1c. We did not find any strong evidence that HIV serostatus influenced HbA1c. The results of our study support incorporating HbA1c into routine clinical blood work in PLWH.
Study context
- Population
- People living with HIV (PLWH) and age- and sex-matched HIV-negative participants recruited from clinics in Brighton, UK
- Participants
- 60 vs 48
- Exposure
- PLWH vs HIV-negative participants
- PLWHn = 60
- HIV-negativen = 48reference
- Outcome
- Influence of HIV serostatus on HbA1c (regression models, separate models for CGM glucose, venous glucose and fructosamine)
Methodological detailsage- and sex-matched, single-centre, Dexcom G6 continuous glucose monitor (CGM) worn for up to 10 days; glucose measured during OGTT; fructosamine and paired HbA1c measured
- Age- and sex-matched
- Single-centre
- Dexcom G6 CGM worn for up to 10 days; glucose measured during OGTT; fructosamine and paired HbA1c measured
Main finding
As reported in the abstract
Influence of HIV serostatus on HbA1c
- HIV serostatus did not have a significant influence on HbA1c within the regression models
Observational data: associations, not effects.
Original publication
What Is the Influence of HIV Serostatus on HbA1c? A Prospective Analysis Using Continuous Glucose Monitoring. Diabetes Care. Published 28 May 2024. doi:10.
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