Weight regain after behavioural weight management programmes and its impact on quality of life and cost effectiveness: Evidence synthesis and health economic analyses
Pooled result · Weight loss at programme endResult — go to the resultDifference −2.8 kg 95% CI −3.2 to −2.4Authors' conclusion
Modest rates of weight regain, with persistent benefits for several years, should encourage health care practitioners and policymakers to offer obesity treatments that cost less than our suggested thresholds as a cost-effective intervention to improve long-term weight management.
Study context
- Population
- Adults with overweight/obesity in randomized trials of behavioural weight management programmes (BWMPs) reporting outcomes at ≥12 months and after programme end (search to December 2019)
- Participants
- > 150,000 adults155 trials
- Comparison
- BWMPs vs control
- Outcome
- Weight loss at programme end
- Follow-up
- Programme end
Methodological detailsmixed-effect, meta-regression and time-to-event models, health sector perspective cost-effectiveness
- Mixed-effect, meta-regression and time-to-event models
- Health sector perspective cost-effectiveness
Pooled result
As reported in the abstract
Difference
−2.8 kg
95% CI −3.2 to −2.4
Interventionvs Control
difference −2.8 kg (95% CI −3.2 to −2.4)
- Weight regain after programme end greater in intervention vs control; between-group difference evident for at least 5 years
- 0.12-0.32 kg/year
Further pooled results
Quality of life
- QoL increased in intervention vs control at programme end, then returned to control as weight difference diminished
Cost-effectiveness
- BWMPs cost-effective if delivered per person for under
- £560 (£8.80-£3900)
Longest follow-up
- Longest follow-up post-programme
- 23 years
Original publication
Weight regain after behavioural weight management programmes and its impact on quality of life and cost effectiveness: Evidence synthesis and health economic analyses. Diabetes Obes Metab. Published 2 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →