Weight Change Between Pregnancies and Mortality Over 50 Years of Follow‐Up
Primary result · All-cause mortalityResult — go to the resultAdjusted hazard ratio 0.85 95% CI 0.76–0.96Authors' conclusion
Minimizing PPWR was linked to reduced mortality risk over 50 years of follow-up.
Study context
- Population
- Women with ≥ 2 pregnancies in the Collaborative Perinatal Project (CPP), U.S., 1959–1966, with vital status follow-up through 2016
- Participants
- 8,165 women
- Comparison
- Quintiles of interconception weight change (ICWC) and interpregnancy weight change (IPWC)
- Primary endpoint
- All-cause mortality
- Follow-up
- Through 2016
Primary result
As reported in the abstract
Adjusted hazard ratio
0.85
95% CI 0.76–0.96
ICWC quintile 2vs ICWC quintile 3
aHR 0.85 (95% CI 0.76–0.96)
Further findings
| Outcome | aHR (95% CI) | |
|---|---|---|
| Diabetes-related mortality | 0.45 (0.23–0.87) | |
| 0.20.5125Adjusted hazard ratio (log scale) |
All-cause and cause-specific mortality by IPWC quintile
- Lower IPWC quintiles (greater weight loss) suggestive of reduced all-cause and cause-specific mortality risk; not statistically significant
Original publication
Weight Change Between Pregnancies and Mortality Over 50 Years of Follow‐Up. Obesity (Silver Spring). Published 20 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →