Weight Change and Accumulation of Chronic Conditions in Women During Reproductive Years
Authors' conclusion
Although weight gain declined after diagnosis, it remained higher than among women without conditions, underscoring the need for improved post-diagnosis weight management.
Study context
- Population
- Women of reproductive age without chronic conditions at baseline, Australian Longitudinal Study on Women's Health; BMI change from Survey 1 (ages 18–23) to Survey 3 (ages 25–30), followed to Survey 9 (ages 43–49)
- Participants
- 8,895 women
- Exposure
- BMI change categories vs stable normal BMI
- Outcome
- Incident multimorbidity
Methodological detailspopulation-based longitudinal, linear mixed models
- Population-based longitudinal
- Linear mixed models
Main finding
As reported in the abstract
Each group vs stable normal BMIOdds ratio (95% CI)
Stable obesity
1.79(1.11–2.90)
Increasing BMI
1.34(1.10–1.63)
Observational data: associations, not effects.
Further findings
Annual weight gain by chronic condition status · Survey 1 to Survey 9
- Free of chronic conditions
- 0.50 kg (0.48, 0.52)
- One condition, overall
- 0.54 kg (0.52, 0.56)
- One condition, before diagnosis
- 0.55 (0.53, 0.57)
- One condition, after diagnosis
- 0.54 (0.51, 0.57)
- Multimorbidity, overall
- 0.65 kg (0.63, 0.67)
- Multimorbidity, before first condition
- 0.75 kg (0.70, 0.80)
- Multimorbidity, between first and second condition
- 0.60 kg (0.56, 0.64)
- Multimorbidity, after second condition
- 0.57 kg (0.53, 0.61)
Original publication
Weight Change and Accumulation of Chronic Conditions in Women During Reproductive Years. Obesity (Silver Spring). Published 2 September 2025. doi:10.
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