Waist‐to‐Height Ratio and the Risk of Cardiovascular Outcomes and Mortality in Type 2 Diabetes With and Without Abdominal Obesity
Authors' conclusion
WHtR was independently associated with cardiovascular outcomes and mortality in individuals with T2DM, including those without abdominal obesity. This simple measurement may provide additional information beyond WC for evaluating cardiometabolic risk in this population.
Study context
- Population
- Patients with T2D who underwent the Korean national health checkup 2015–2016, followed until 2022
- Participants
- 2,076,104 patients
- Exposure
- Waist-to-height ratio (WHtR) categories stratified by abdominal obesity
- Outcome
- Incident MI, stroke and mortality
- Follow-up
- Until 2022
Methodological detailsmultivariable Cox proportional hazards regression, restricted cubic spline analyses
- Multivariable Cox proportional hazards regression
- Restricted cubic spline analyses
Main finding
As reported in the abstract
MI, stroke and all-cause mortality
Abdominal obesity + WHtR ≥ 0.5: MI HR
1.12
95% CI 1.07–1.17
Abdominal obesity + WHtR ≥ 0.5: stroke HR
1.18
95% CI 1.15–1.21
Abdominal obesity + WHtR ≥ 0.5: mortality HR
1.20
95% CI 1.16–1.25
Observational data: associations, not effects.
Further findings
Events during follow-up
- Deaths
- 125 493 (6.0%)
- MI
- 56 280 (2.7%)
- Strokes
- 62 938 (3.0%)
Subgroups by age and T2D duration
- Associations stronger in younger adults and new-onset T2D for cardiovascular outcomes, and in long-standing T2D for mortality
Original publication
Waist‐to‐Height Ratio and the Risk of Cardiovascular Outcomes and Mortality in Type 2 Diabetes With and Without Abdominal Obesity. Diabetes Obes Metab. Published 24 March 2026. doi:10.
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