Thyroid disease

Voice and swallowing symptoms after thyroid surgery assessed using the ThyVoice online platform

Eur Thyroid JPublished Prospective multicentre cohort study

Authors' conclusion

The ThyVoice online platform allows the assessment of patient-reported outcome measures in thyroid surgery. Voice morbidity appears to be more frequent than commonly reported, and this risk should the quoted during informed consent. Swallowing difficulties are mild but significant in the first 2 weeks.

Study context

Population
Patients undergoing thyroid surgery, 5 centres
Participants
236 patients5 centres
Outcome
Progression of patient-reported voice and swallowing outcomes (VHI, VrQoL, EAT-10)
Follow-up
Preop, 2-6 weeks and 3-6-12 months after surgery
Methodological detailsonline platform (ThyVoice), patient-reported outcomes, Contributing centres: median 11 cases (range 2-186)
  • Online platform (ThyVoice)
  • Patient-reported outcomes
  • Contributing centres: median 11 cases (range 2-186)

Main finding

As reported in the abstract

VHI preop
41 ± 15
VHI at 6 weeks
48 ± 21
VHI at 6 months
41 ± 15
VrQoL preop
12 ± 4
VrQoL increased to
15 ± 6
VrQoL at 6 months
12 ± 4
Severe voice changes (VHI > 60) preop
12%
Severe voice changes at 2 weeks
22%
Severe voice changes at 6 weeks
18%
Severe voice changes at 3 months
13%
Severe voice changes at 12 months
7%
EAT-10 swallowing score preop, median (IQR)
0 (0-3)
EAT-10 swallowing score at 2 weeks, median (IQR)
2 (0-8)
Swallowing scores after 2 weeks
normal values

Observational data: associations, not effects.

Further findings

Persistent severe voice changes after 6-12 months in patients with normal preop voice

Patients
5

VHI in patients with severe voice changes at 2 weeks · 2 weeks to 6 months

Median VHI at 2 weeks (IQR)
70.5 (65-81)
Median VHI at 6 months (IQR)
54 (39-65)
Significant improvement
P < 0.001

Original publication

Voice and swallowing symptoms after thyroid surgery assessed using the ThyVoice online platform. Eur Thyroid J. Published 21 June 2023. doi:10.1530/etj-23-0008

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