Obesity

Utilization and outcomes of nutrient-stimulated hormone therapies in patients undergoing bariatric surgery

Int J Obes (Lond)Published Retrospective cohort study

Authors' conclusion

Individuals who underwent RYGB and who did not have diabetes had the highest %TWL. Receiving a NuSH prescription both before and after surgery and early NuSH initiation were associated with the greatest %TWL.

Study context

Population
Adults who underwent bariatric surgery at a single academic medical center, 2015–2022
Participants
1,638 adults
Exposure
Nutrient-stimulated hormone (NuSH) prescriptions before and after surgery vs only after surgery vs no prescriptions
Outcome
%TWL over time
Methodological detailssingle academic medical center, linear mixed models
  • Single academic medical center
  • Linear mixed models

Main finding

As reported in the abstract

Adjusted average %TWL · 72 months

Observational data: associations, not effects.

Further findings

%TWL by surgery type

RYGB had greater %TWL vs sleeve gastrectomy (SG)

%TWL by diabetes status

Those without diabetes had greater %TWL vs those with diabetes

%TWL by timing of NuSH initiation

Greatest %TWL with prescriptions within 6 months after surgery

Original publication

Utilization and outcomes of nutrient-stimulated hormone therapies in patients undergoing bariatric surgery. Int J Obes (Lond). Published 20 July 2026. doi:10.1038/s41366-026-02159-3

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