Endocrine oncology

Ultrasound‐guided thermal ablation for papillary thyroid microcarcinoma: A systematic review

Clin Endocrinol (Oxf)Published Systematic review

Authors' conclusion

TA is an effective alternative method for surgery in the treatment of low-risk PTMC and has the advantages of being minimally invasive, economical, having less bleeding and having a high postoperative quality of life.

Study context

Population
Patients with papillary thyroid microcarcinoma (PTMC) treated with thermal ablation27 articles
Comparison
Ultrasound-guided thermal ablation for PTMC
Outcome
Indications, efficacy and safety of TA for PTMC
Methodological detailsPRISMA, Literature search until January 2022
  • PRISMA
  • Literature search until January 2022

Pooled result

As reported in the abstract

  • Indications of thermal ablation (TA) for PTMC divided into six primary and three secondary indications
  • Volume reduction rate highest after radiofrequency ablation (RFA), followed by microwave ablation and laser ablation (LA)
  • Improvement in quality of life significantly better after TA than after thyroidectomy
  • Rapid recovery after RFA, with no major complications, recurrence or lymph node metastasis

Safety

No major complications after RFA
LA is safe to important organs around the lesion

Original publication

Ultrasound‐guided thermal ablation for papillary thyroid microcarcinoma: A systematic review. Clin Endocrinol (Oxf). Published 12 December 2022. doi:10.1111/cen.14857

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