UK cost-effectiveness analysis of endoscopic sleeve gastroplasty versus lifestyle modification alone for adults with class II obesity
Main finding · ICERResult — go to the resultICER £2453/QALY gainedAuthors' conclusion
Our study indicates that ESG is highly cost effective versus LM alone for the treatment of adults with class II obesity in England.
Study context
- Population
- Adults with class II obesity (BMI 35.0–39.9 kg/m²), England; inputs from the class II obesity subset of MERIT
- Comparison
- Endoscopic sleeve gastroplasty (ESG) vs lifestyle modification (LM) alone
- Outcome
- ICER for ESG vs LM alone (cost per QALY gained)
Methodological details6-state Markov model, national healthcare system perspective (England), based on patient-level data from MERIT RCT, probabilistic sensitivity analysis
- 6-state Markov model
- National healthcare system perspective (England)
- Based on patient-level data from MERIT RCT
- Probabilistic sensitivity analysis
Main finding
ICER
Incremental cost-effectiveness ratio (ICER)
£2453/QALY gained
As reported in the abstract
Further findings
Deterministic sensitivity analyses
- ESG consistently cost effective; no ICER estimate exceeding
- £10,000/QALY gained
Probabilistic sensitivity analysis
- Mean ICER
- £2502/QALY gained
- ESG cost effective at willingness-to-pay threshold of £20,000/QALY, % of iterations
- 98.25%
Original publication
UK cost-effectiveness analysis of endoscopic sleeve gastroplasty versus lifestyle modification alone for adults with class II obesity. Int J Obes (Lond). Published 6 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →