Type-2 diabetes mellitus remission prediction models after Roux-En-Y gastric bypass and sleeve gastrectomy based on disease severity scores
Authors' conclusion
We demonstrate the ability of the IMS, DiaRem, advanced-DiaRem and Robert et al. scores to predict T2DM remission in patients undergoing MBS. T2DM remission rates was demonstrated to decrease with more severe IMS, DiaRem and advanced-DiaRem scores and lower Robert et al. scores.
Study context
- Population
- Patients with T2D undergoing RYGB (78 %) or sleeve gastrectomy (SG); 67 % females, mean age 53.5 [11] years, BMI 46.2 [8.8] kg/m²
- Participants
- 503 patients
- Exposure
- Individualized Metabolic Surgery (IMS) vs DiaRem vs advanced-DiaRem vs Robert et al. scores for predicting T2D remission
- Outcome
- Discriminatory ability (ROC AUC) of the four models to detect T2D remission after metabolic and bariatric surgery (MBS)
Methodological detailsvalidation of prediction models
- Validation of prediction models
Main finding
As reported in the abstract
T2D remission prediction
| Group | AUC |
|---|---|
| IMS | 0.79 |
| DiaRem | 0.78 |
| Advanced-DiaRem | 0.78 |
| Robert et al. | 0.75 |
AUC
IMS0.79
DiaRem0.78
Advanced-DiaRem0.78
Robert et al.0.75
Observational data: associations, not effects.
Further findings
T2D remission by procedure within score subgroups
- Specific subgroups for each score had higher T2D remission rates after RYGB vs SG
Original publication
Type-2 diabetes mellitus remission prediction models after Roux-En-Y gastric bypass and sleeve gastrectomy based on disease severity scores. Diabetes Res Clin Pract. Published 13 January 2024. doi:10.
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