Type 2 diabetes complications in ethnic minority compared with European host populations: a systematic review and meta-analysis
Authors' conclusion
Ethnic minority populations with T2D in Europe are generally at reduced risk of all-cause mortality and macrovascular complications, but at higher risk of nephropathy and retinopathy.
Study context
- Population
- People with T2D in Europe; ethnic minority vs host populations; studies until July 1, 202458 studies
- Comparison
- Ethnic minority vs European host populations with T2D
- Outcome
- T2D complications: mortality, macrovascular and microvascular complications and mental disorders
Methodological detailscross-sectional and prospective studies, random effects models, PRISMA guidelines, 805 to 1 230 410 individuals for the meta-analyzed complications, Risk of bias assessed with the tool for observational cohort and cross-sectional studies
- Cross-sectional and prospective studies
- Random effects models
- PRISMA guidelines
- 805 to 1 230 410 individuals for the meta-analyzed complications
- Risk of bias assessed with the tool for observational cohort and cross-sectional studies
Pooled result
As reported in the abstract
T2D complications
Ethnic minority vs Host populationRelative risk (95% CI)
All-cause mortality; I2=87%
0.70(0.63–0.77)
Macrovascular complications; I2=88%
0.72(0.58–0.88)
- Increased risks for microvascular complications, nephropathy and retinopathy; nephropathy in prospective studies
- RR 1.50 (95% CI 1.14; 1.96); I2=86%
Further pooled results
- South Asians showed comparable risks for most macrovascular complications and a slightly higher risk of MACE
Original publication
Type 2 diabetes complications in ethnic minority compared with European host populations: a systematic review and meta-analysis. BMJ Open Diabetes Res Care. Published 7 November 2024. doi:10. 1136/ bmjdrc-2024-004345
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