Type 2 & other diabetes

Type 2 Diabetes and Its Association With Psychiatric Disorders in Young Adults in South Korea

JAMA Netw OpenPublished Prospective cohort study

Main finding · T2D incidenceResult — go to the resultAdjusted hazard ratio 1.20 95% CI 1.17–1.22

Authors' conclusion

In this large-scale prospective cohort study of young adults, 5 psychiatric disorders were significantly associated with an increased risk of developing T2D. Young adults with schizophrenia and bipolar disorder in particular were at a higher risk of T2D. These results have important implications for early detection of and timely intervention in T2D for young adults with psychiatric disorders.

Study context

Population
Young adults aged 20–39 years without history of T2D, South Korean National Health Insurance Service data 2009–2012; mean age 30.74 years, 59.18% men
Participants
6,457,991 adults
Exposure
Psychiatric disorder vs no psychiatric disorder
  • Psychiatric disordersn = 658,430
Outcome
Newly diagnosed T2D
Follow-up
7.59 years
Methodological detailslarge-scale, nationwide
  • Large-scale
  • Nationwide

Main finding

T2D incidence

Adjusted hazard ratio

1.20

95% CI 1.17–1.22

By group

Psychiatric disordersvs Without psychiatric disorders
aHR 1.20 (95% CI 1.17–1.22)

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeaHR (95% CI)
T2D risk by psychiatric disorderSchizophreniavs Without psychiatric disorders2.04 (1.83–2.28)
T2D risk by psychiatric disorderBipolar disordervs Without psychiatric disorders1.91 (1.73–2.12)
T2D risk by psychiatric disorderDepressive disordervs Without psychiatric disorders1.24 (1.20–1.28)
T2D risk by psychiatric disorderAnxiety disordervs Without psychiatric disorders1.13 (1.11–1.16)
T2D risk by psychiatric disorderSleep disordervs Without psychiatric disorders1.31 (1.27–1.35)

Original publication

Type 2 Diabetes and Its Association With Psychiatric Disorders in Young Adults in South Korea. JAMA Netw Open. Published 1 June 2023. doi:10.1001/jamanetworkopen.2023.19132

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