Type 2 Diabetes and Its Association With Psychiatric Disorders in Young Adults in South Korea
Main finding · T2D incidenceResult — go to the resultAdjusted hazard ratio 1.20 95% CI 1.17–1.22Authors' conclusion
In this large-scale prospective cohort study of young adults, 5 psychiatric disorders were significantly associated with an increased risk of developing T2D. Young adults with schizophrenia and bipolar disorder in particular were at a higher risk of T2D. These results have important implications for early detection of and timely intervention in T2D for young adults with psychiatric disorders.
Study context
- Population
- Young adults aged 20–39 years without history of T2D, South Korean National Health Insurance Service data 2009–2012; mean age 30.74 years, 59.18% men
- Participants
- 6,457,991 adults
- Exposure
- Psychiatric disorder vs no psychiatric disorder
- Psychiatric disordersn = 658,430
- Outcome
- Newly diagnosed T2D
- Follow-up
- 7.59 years
Methodological detailslarge-scale, nationwide
- Large-scale
- Nationwide
Main finding
T2D incidence
Adjusted hazard ratio
1.20
95% CI 1.17–1.22
By group
Psychiatric disordersvs Without psychiatric disorders
aHR 1.20 (95% CI 1.17–1.22)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | aHR (95% CI) | |
|---|---|---|
| T2D risk by psychiatric disorderSchizophreniavs Without psychiatric disorders | 2.04 (1.83–2.28) | |
| T2D risk by psychiatric disorderBipolar disordervs Without psychiatric disorders | 1.91 (1.73–2.12) | |
| T2D risk by psychiatric disorderDepressive disordervs Without psychiatric disorders | 1.24 (1.20–1.28) | |
| T2D risk by psychiatric disorderAnxiety disordervs Without psychiatric disorders | 1.13 (1.11–1.16) | |
| T2D risk by psychiatric disorderSleep disordervs Without psychiatric disorders | 1.31 (1.27–1.35) | |
| 0.512Adjusted hazard ratio (log scale) |
Original publication
Type 2 Diabetes and Its Association With Psychiatric Disorders in Young Adults in South Korea. JAMA Netw Open. Published 1 June 2023. doi:10. 1001/ jamanetworkopen. 2023. 19132
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