Type 1 diabetes

The Type 1 Diabetes T Cell Receptor and B Cell Receptor Repository in the Adaptive Immune Receptor Repertoire (AIRR) Data Commons: a practical guide for access, use and contributions through the Type 1 Diabetes AIRR Consortium

DiabetologiaPublished Data repository description

Study context

Population
Type 1 diabetes T cell receptor (TCR) and B cell receptor (BCR) sequence datasets with detailed metadata (participant demographics, disease-associated parameters, tissue type)
Methodological detailspractical guide
  • Practical guide

Main finding

As reported in the abstract

  • Created the T1D TCR/BCR Repository to study highly variable, dynamic TCR and BCR gene rearrangements (AIRR) in T1D
  • Repository includes processed TCR and BCR sequences plus detailed metadata (participant demographics, disease-associated parameters, tissue type)
  • Introduces the Type 1 Diabetes AIRR Consortium goals and methods to use and deposit data

Original publication

The Type 1 Diabetes T Cell Receptor and B Cell Receptor Repository in the AIRR Data Commons: a practical guide for access, use and contributions through the Type 1 Diabetes AIRR Consortium. Diabetologia. Published 29 October 2024. doi:10.1007/s00125-024-06298-y

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