Twenty‐four‐hour physical behaviour profiles across type 2 diabetes mellitus subtypes
Authors' conclusion
In individuals living with T2DM, the OB subtype had the lowest levels of physical activity and least favourable sleep profiles. Such behaviours may be suitable targets for personalized therapeutic lifestyle interventions.
Study context
- Population
- Adults living with T2D in an ongoing observational study; mean age 63.6 ± 8.4 years, 37.6% female, mean age at diagnosis 53.1 ± 10.0 years
- Participants
- 564 adults
- Exposure
- T2D subtypes vs AGE cluster
- INS-Dn = 35
- INS-Rn = 88
- OBn = 166
- AGEn = 275reference
- Outcome
- 24-h physical behaviours (sleep, physical activity, sedentary time) measured by accelerometer
- Follow-up
- 7 days
Methodological detailsaccelerometer for 7 days, k-means clustering, generalized linear models
- Accelerometer for 7 days
- K-means clustering
- Generalized linear models
Main finding
As reported in the abstract
24-h physical behaviours, OB vs AGE
OB vs AGESleep efficiency difference, % (95% CI)
24-h physical behaviours, OBvs AGE
−2(−3 to −1)
OB vs AGETotal physical activity difference, mg (95% CI)
24-h physical behaviours, OBvs AGE
−2.9(−4.3 to −1.6)
OB vs AGEEstimate (95% CI)
Less with OB
moderate-to-vigorous physical activity time difference −6.6 min(−11.4 to −1.7)
24-h physical behaviours, OBvs AGE
sleep variability difference 17.9 min(8.2–27.7)
24-h physical behaviours, OBvs AGE
sedentary time difference 31.9 min(10.5–53.2)
- Shorter with OB
- sleep duration difference −0.3 h (95% CI −0.5 to −0.1)
Observational data: associations, not effects.
Original publication
Twenty‐four‐hour physical behaviour profiles across type 2 diabetes mellitus subtypes. Diabetes Obes Metab. Published 8 January 2024. doi:10.
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