Obesity

Trimester‐specific rate of gestational weight loss or gain and birth size: differences by prepregnancy BMI

Obesity (Silver Spring)Published Cohort study

Authors' conclusion

Among people with prepregnancy obesity class II or III, GWG rate is associated with higher LGA risk in a dose-dependent manner, including understudied ranges of weight loss, but with weak associations with SGA.

Study context

Population
Pregnancies in a national network of community health care organizations
Participants
20,676 / 19,156 / 11,647 / 5,124 / 3,197
Exposure
Trimester-specific gestational weight gain (GWG) rate across prepregnancy BMI categories
  • Normal weightn = 20,676
  • Overweightn = 19,156
  • Obesity class In = 11,647
  • Obesity class IIn = 5,124
  • Obesity class IIIn = 3,197
Outcome
SGA and LGA (vs AGA) by trimester 1, 2 or 3 GWG rate
Methodological detailsstratified by prepregnancy BMI, modified Poisson regression
  • Stratified by prepregnancy BMI
  • Modified Poisson regression

Main finding

As reported in the abstract

GWG-LGA associations strongest in trimester 1; RR range for 10th vs 50th percentile GWG, across BMI categories

0.60-0.73

GWG-SGA associations strongest in lower BMI categories and in trimester 2; RR, Normal weight

1.62

GWG-SGA RR, trimester 2, Obesity class I

1.40

GWG-SGA RR, trimester 2, Obesity class III

1.17

Observational data: associations, not effects.

Original publication

Trimester‐specific rate of gestational weight loss or gain and birth size: differences by prepregnancy BMI. Obesity (Silver Spring). Published 30 July 2024. doi:10.1002/oby.24071

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