Weight gain patterns among pregnancies with obesity and small‐ and large‐for‐gestational‐age births
Authors' conclusion
Second- and third-trimester weight maintenance may be associated with more optimal birth weight for gestational age. However, how this could be achieved (e.g., through diet and exercise interventions) is unclear, given the observational design of our study.
Study context
- Population
- Pregnancies with obesity, class I (30–34.9 kg/m²), II (35–39.9 kg/m²), III (≥40 kg/m²); Magee-Womens Hospital, Pittsburgh, Pennsylvania, 1998–2011; subcohort 1290, 1247 and 1198 pregnancies; Small-for-gestational-age (SGA) cases 262, 171, 123; Large-for-gestational-age (LGA) cases 353, 286, 257 for classes I, II, III
- Exposure
- Second- and third-trimester gestational weight gain (GWG) trajectories (maintenance, higher, highest) vs approximating IOM recommendations; first-trimester GWG below/above vs within recommendations
- Outcome
- SGA and LGA births
Methodological detailsstratified by obesity class
- Stratified by obesity class
Main finding
As reported in the abstract
LGA and SGA births, class III, second- and third-trimester weight maintenance
Maintenance vs RecommendationsRelative risk (95% CI)
LGA, class III
0.80(0.55–1.1)
SGA, class III
0.98(0.64–1.5)
Observational data: associations, not effects.
Further findings
SGA risk with second- and third-trimester weight maintenance, classes I and II (sensitivity analyses)
- Some sensitivity analyses supported no increased SGA risk with maintenance for classes I and II
Original publication
Weight gain patterns among pregnancies with obesity and small‐ and large‐for‐gestational‐age births. Obesity (Silver Spring). Published 21 March 2023. doi:10.
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