Risk related to gestational weight loss among individuals with obesity: a population‐based cohort study
Main finding · Composite of adverse perinatal outcomesResult — go to the resultAdjusted risk ratio 1.31 95% CI 1.22–1.39Authors' conclusion
Our findings suggest that GWL may increase the risk of adverse perinatal outcomes across all obesity classes.
Study context
- Population
- Individuals with prepregnancy BMI ≥ 30 kg/m² and a singleton pregnancy, Ontario, Canada, birth registry 2012–20206.1% with gestational weight loss (GWL)
- Participants
- 157,205 individuals
- Exposure
- GWL vs adequate gestational weight gain
- Outcome
- Composite of:
- Adverse outcomes
- Including perinatal death
- Neonatal morbidity
Methodological detailsbirth registry data, stratified by obesity class
- Birth registry data
- Stratified by obesity class
Main finding
Composite of adverse perinatal outcomes
Adjusted risk ratio
1.31
95% CI 1.22–1.39
GWLvs Adequate gestational weight gain
adjusted risk ratio 1.31 (95% CI 1.22–1.39)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Composite of adverse perinatal outcomes, stratified by obesity class
- Similar results were observed in the stratified analysis
Average weekly gestational weight change (restricted cubic spline)
- Nonlinear U-shaped association, with higher risk of composite adverse perinatal outcomes at the extremities, particularly toward GWL and excessive weight gain
Original publication
Risk related to gestational weight loss among individuals with obesity: a population‐based cohort study. Obesity (Silver Spring). Published 5 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →