Triglyceride-glucose index predicts adverse cardiovascular events in patients with H-type hypertension combined with coronary heart disease: a retrospective cohort study
Authors' conclusion
The TyG index may be an independent risk factor for predicting adverse postoperative cardiovascular events in patients with H-type hypertension combined with CHD, indicating its potential significance in improving risk stratification strategies.
Study context
- Population
- Patients with H-type hypertension combined with coronary heart disease (CHD), Beijing Anzhen Hospital, 2018–2023
- Participants
- 546 patients73 major adverse cardiovascular events (MACEs)
- Exposure
- TyG index tertiles
- Outcome
- MACE
- Follow-up
- Median 39.00 ± 0.69 months
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Fully adjusted OR (95% CI)
T2vs T1
1.64(0.80–3.36)
T3vs T1
2.43(1.19–4.97)
- Higher TyG tertiles associated with higher cumulative risk of MACE (log-rank)
- P = 0.001
Observational data: associations, not effects.
Further findings
Incremental predictive ability of TyG index added to baseline model
- C-statistic increased from 0.63 to 0.66
- P = 0.031
- Continuous NRI 0.13 (95% CI 0.001-0.276)
- P = 0.038
- IDI 0.01 (95% CI 0.000-0.031)
- P = 0.047
Original publication
Triglyceride-glucose index predicts adverse cardiovascular events in patients with H-type hypertension combined with coronary heart disease: a retrospective cohort study. Cardiovasc Diabetol. Published 29 January 2025. doi:10.
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