Triglyceride-glucose index: a novel evaluation tool for all-cause mortality in critically ill hemorrhagic stroke patients-a retrospective analysis of the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database
Authors' conclusion
In summary, TyG-i exhibits a significant correlation with ACM among patients enduring critical illness due to HS. This correlation underscores the probable utility of TyG-i as a prognostic tool for stratifying HS patients according to their risk of mortality. Applying TyG-i in clinical settings could enhance therapeutic decision-making and the management of disease trajectories. Additionally, this investigation augments existing research on the linkage between the TyG-i and IS, elucidating the TyG-i's role in predicting mortality across diverse stroke categories.
Study context
- Population
- Critically ill patients with severe hemorrhagic stroke (non-traumatic intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH)) admitted to intensive care unit (ICU), MIMIC-IV (version 2.2) database54.4% male
- Participants
- 1,475 patients
- Exposure
- Higher vs lower triglyceride-glucose index (TyG-i)
- Outcome
- Association of TyG-i with ACM among critically ill hemorrhagic stroke (HS) patients in the ICU
Methodological detailsMIMIC-IV database, TyG-i quartiles
- MIMIC-IV database
- TyG-i quartiles
Main finding
As reported in the abstract
aHR 30 days
1.32
95% CI 1.05–1.67P = 0.020
aHR 90 days
1.27
95% CI 1.04–1.55P = 0.019
aHR 1 year
1.22
95% CI 1.03–1.44P = 0.023
Observational data: associations, not effects.
Further findings
Observed mortality, whole cohort
- ICU
- 7.3%
- In-hospital
- 10.9%
- 30 days
- 13.8%
- 90 days
- 19.7%
- 1 year
- 27.3%
Original publication
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