Triglyceride-glucose Index and Mortality in a Large Regional-based Italian Database (URRAH Project)
Authors' conclusion
The results of this study indicate that these TyG (a low-cost and simple, noninvasive marker) thresholds are predictive of an increased risk of mortality in a large and homogeneous general population. In addition, these results show a synergic effect of TyG and SUA on the risk of mortality.
Study context
- Population
- General population, URRAH cohort (Italy)URRAH cohort
- Participants
- 16,649 participants
- Exposure
- Triglyceride-glucose (TyG) index above vs below optimal cut-off
- Outcome
- All-cause and CV mortality
- Follow-up
- Median 144 months
Methodological detailsregional-based database, general population
- Regional-based database
- General population
Main finding
As reported in the abstract
Deaths
2569
Observational data: associations, not effects.
Further findings
Combined TyG and serum uric acid (SUA)
- Simultaneous high TyG and SUA associated with higher mortality risk than none or only 1 of the 2 factors
Original publication
Triglyceride-glucose Index and Mortality in a Large Regional-based Italian Database (URRAH Project). J Clin Endocrinol Metab. Published 14 March 2024. doi:10.
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