Trends in the Incidence of Type 1 Diabetes in European Children and Adolescents from 1994 to 2022: A Systematic Review and Meta-Analysis
Authors' conclusion
There are substantial between-country differences in the current levels and trends of IR in type 1 diabetes in European children and adolescents. Our data suggest a worrying upward trend in most European countries.
Study context
- Population
- European children and adolescents diagnosed with T1D aged <15 years; cross-sectional or follow-up studies reporting population-based incidence rates; 32 countries
- Participants
- 219,331 children75 studies
- Comparison
- Incidence of T1D in 1994–2003 vs 2013–2022
- Outcome
- Pooled incidence rate of T1D
- Follow-up
- 1994 to 2022
Methodological detailsrandom-effects (Mantel-Haenszel or DerSimonian and Laird), population-based incidence studies, subgroup analyses by study year, sex, age group, country and European region
- Random-effects (Mantel-Haenszel or DerSimonian and Laird)
- Population-based incidence studies
- Subgroup analyses by study year, sex, age group, country and European region
Pooled result
As reported in the abstract
Pooled T1D incidence rate
1994 to 2003
10.85 per 100,000 person-years
CI 9.62–12.07
2013 to 2022
20.96 per 100,000 person-years
CI 19.26–22.66
Original publication
Trends in the Incidence of Type 1 Diabetes in European Children and Adolescents from 1994 to 2022: A Systematic Review and Meta-Analysis. Pediatr Diabetes. Published 27 May 2024. doi:10.
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