Trends and Inequalities in Diabetes-Related Complications Among U.S. Adults, 2000–2020
Authors' conclusion
There was a continued increase of several complications in the past decade. Age, sex, and racial and ethnic inequalities have worsened for some complications.
Study context
- Population
- U.S. adults (≥18 years) with diagnosed diabetes, 2000–2020; National (Nationwide) Inpatient Sample, United States Renal Data System, National Health Interview Survey
- Outcome
- Trends in diabetes-related complications (HF, MI, stroke, ESRD, NLEA, hyperglycemic crisis) by age-group, race and ethnicity, and sex, and trends in inequalities
- Follow-up
- 2000-2020
Methodological detailsnational trends, joinpoint-style annual percent change analysis
- National trends
- Joinpoint-style annual percent change analysis
Main finding
As reported in the abstract
Hospitalization rates / ESRD incidence trends (APC)
- HF hospitalizations, 2012-2020 annual percent change (APC) (P < 0.001)
- 3.9%
- Stroke hospitalizations, 2009-2020 APC (P < 0.001)
- 2.8%
- NLEA hospitalizations, 2009-2020 APC (P < 0.001)
- 5.9%
- ESRD incidence, 2010-2020 APC (P = 0.044)
- 1.0%
- Hyperglycemic crisis, 2000 to 2020 APC (P < 0.001)
- 2.2%
- MI hospitalizations, 2000-2008 APC (P < 0.001); flat thereafter
- −6.0%
Observational data: associations, not effects.
Further findings
- Age inequalities declined on average for HF, MI, stroke hospitalizations and ESRD incidence; increased for hyperglycemic crisis
- Sex inequalities increased on average for stroke and NLEA hospitalizations and ESRD incidence
- Racial and ethnic inequalities declined 2012-2020 for ESRD incidence; increased for HF, stroke and hyperglycemic crisis
Original publication
Trends and Inequalities in Diabetes-Related Complications Among U.S. Adults, 2000–2020. Diabetes Care. Published 21 June 2024. doi:10. 2337/ dci24-0022
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